posted on 2023-02-01, 15:00authored byAlyssa KaganerAlyssa Kaganer, Robert J. Ossiboff, Nicole I. Keith, Krysten L. Schuler, Pierre Comizzoli, Matthew Hare, Robert Fleischer, Brian Gratwicke, Elizabeth M. Bunting
<p>In this study, we explored the efficacy of Bd
vaccination on hellbender salamanders and functionally characterized host,
host-associated microbiome, and pathogen throughout immunization and infection.
We compared the function of hellbender skin, the skin microbiome, and Bd with a
metatranscriptome approach at four experimental time points, (i)
pre-vaccination and pre-infection, (ii) post-vaccination and pre-infection,
(iii) early infection, and (iv) late infection.</p>