posted on 2023-02-01, 14:58authored byAlyssa KaganerAlyssa Kaganer, Robert J. Ossiboff, Nicole I. Keith, Krysten L. Schuler, Pierre Comizzoli, Matthew
P. Hare, Robert C. Fleischer, Brian Gratwicke, Elizabeth M. Bunting
In
this study, we explored the efficacy of Bd vaccination on hellbender
salamanders and functionally characterized host, host-associated microbiome,
and pathogen throughout immunization and infection. We compared the function of
hellbender skin, the skin microbiome, and Bd with a metatranscriptome approach
at four experimental time points, (i) pre-vaccination and pre-infection, (ii)
post-vaccination and pre-infection, (iii) early infection, and (iv) late
infection.