The Smithsonian Institution

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HellbenderSkinProkaryoteTranscriptome_Trinity.fasta.gz (13.55 MB)

Hellbender skin prokaryote transcriptome

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posted on 2023-02-01, 14:58 authored by Alyssa KaganerAlyssa Kaganer, Robert J. Ossiboff, Nicole I. Keith, Krysten L. Schuler, Pierre Comizzoli, Matthew P. Hare, Robert C. Fleischer, Brian Gratwicke, Elizabeth M. Bunting

In this study, we explored the efficacy of Bd vaccination on hellbender salamanders and functionally characterized host, host-associated microbiome, and pathogen throughout immunization and infection. We compared the function of hellbender skin, the skin microbiome, and Bd with a metatranscriptome approach at four experimental time points, (i) pre-vaccination and pre-infection, (ii) post-vaccination and pre-infection, (iii) early infection, and (iv) late infection.