posted on 2023-02-01, 14:59authored byAlyssa KaganerAlyssa Kaganer, Robert J. Ossiboff, Nicole I. Keith, Krysten L. Schuler, Pierre Comizzoli, Matthew
P. Hare, Robert C. Fleischer, Brian Gratwicke, Elizabeth M. Bunting
<p>In
this study, we explored the efficacy of Bd vaccination on hellbender
salamanders and functionally characterized host, host-associated microbiome,
and pathogen throughout immunization and infection. We compared the function of
hellbender skin, the skin microbiome, and Bd with a metatranscriptome approach
at four experimental time points, (i) pre-vaccination and pre-infection, (ii)
post-vaccination and pre-infection, (iii) early infection, and (iv) late
infection.</p>