posted on 2023-02-01, 15:00authored byAlyssa KaganerAlyssa Kaganer, Robert J. Ossiboff, Nicole I. Keith, Krysten L. Schuler, Pierre Comizzoli, Matthew
P. Hare, Robert C. Fleischer, Brian Gratwicke, Elizabeth M. Bunting
In this study, we explored the efficacy of Bd
vaccination on hellbender salamanders and functionally characterized host,
host-associated microbiome, and pathogen throughout immunization and infection.
We compared the function of hellbender skin, the skin microbiome, and Bd with a
metatranscriptome approach at four experimental time points, (i)
pre-vaccination and pre-infection, (ii) post-vaccination and pre-infection,
(iii) early infection, and (iv) late infection.