posted on 2024-05-07, 14:16authored byMircea Podar, Cynthia GilmourCynthia Gilmour, Craig C. Brandt, Allyson Soren, Steven D. Brown, Bryan R. Crable, Anthony V. Palumbo, Anil C. Somenahally
Table S1. List of metagenomic projects with hgcA counts.
Table S2. Identity matrix of sequence similarities.
Fig. S1. Whisker plot distribution of genomic and metagenomic PFam3599 protein hits to various hidden Markov profiles.
Fig. S2. Distribution of HgcA and WL pathway–associated CFeSP encoding genes in methanogenic Archaea.
Fig. S3. Distribution of HgcA, HgcB, and WL pathway–associated CFeSP in genomes of Deltaproteobacteria and Firmicutes.
Fig. S4. Hg methylation assays for M. luminyensis B10.
Fig. S5. Repeat methylation assay for M. luminyensis B10.
Fig. S6. Schematic representation of the domain architectures of HgcA, HgcB, and the fusion HgcAB.
Fig. S7. Hg methylation assays for P. furiosus.
Fig. S8. MEGAN-based co-occurrence profiles of the closest genera-assigned HgcAs based on all metagenomes.